Seminars & Workshops
Cardiac Cachexia Across Species

How can veterinarians and physicians collaborate to solve health problems?

Learn about a practical example of One Health, a multi-disciplinary approach to address a common and serious health condition, at Tufts Medical Center’s Medical Ground Rounds on October 5.

Lisa Freeman, DVM, PhD, DACVN, Director of Tufts CTSI One Health Program and Amanda Vest, MBBS, MPH, Medical Director, Cardiac Transplantation Program, will discuss their research collaboration for improved diagnosis and treatment of cardiac cachexia, a complex wasting condition recognized in as many as 20-50% of humans with systolic heart failure and in similar numbers of pet dogs with spontaneously-occurring heart failure.

This one-hour seminar will present current challenges in the clinic and research, and novel opportunities to identify cardiac cachexia earlier and to treat it more effectively through One Health methods.

After the seminar, participants will be able to:

  • Recognize similarities and differences in cardiac cachexia across species.
  • Describe the mechanisms underlying cardiac cachexia.
  • List methods for diagnosing cardiac cachexia.
  • Discuss the potential benefits of cross-species research in developing strategies for treating cardiac cachexia.


Friday, October 5, 2018, 12:00-1:00PM
Wolff Auditorium, Tufts Medical Center, 800 Washington Street, Boston

You are welcome to bring your own lunch.

This Grand Rounds is designed by Tufts CTSI, an NIH-funded research services organization for the Tufts community and beyond.


Registration is not required.

Seminars & Workshops
Environmental Aspects of One Health

After completing this lecture, you will be able to:

  • Define what is the geography of risk
  • Describe the One Health Enviromental connection
  • Using the examples, explain how the enviroment is impacted in the One Health framework.

Taught by: Christine L. Rioux, PhD, MS, and Antje M. F. Danielson, PhD.

Seminars & Workshops
Healthy Pets Helping People: the Healthcare Community’s Role in Safe and Effective Animal-Assisted Therapy

After completing this lecture, you will be able to:

  • List the benefits of animal assisted interventions
  • Explain how human-animal interactions can provide both psychological and physiological benefits to humans
  • Describe examples of current reserach initiatives in human-animal interactions.

Taught by: Deborah Linder, DVM, DACVN and Megan Mueller, MA, PhD.

Seminars & Workshops
Natural Animal Models: Beyond Rats and Mice

After completing this lecture, you will be able to:

  • Discuss how One Health can support, extend, and validate translational research
  • Describe the ways in which animal models can translate basic science research into human clinical trials
  • Explain how animal models are used to further T1 research.

Taught by: Andrew Hoffman, DVM, DVSc, DACVIM, Elizabeth McNiel, DVM, PhD, DACVIM, DACVR, and Nicholas Frank, DVM, PhD.

Conferences & Symposia
One Health Symposium

One Health Symposium Slides (PDF)

Interested in Integrating Human, Animal and Environmental Health?

Want to meet collaborators and develop grant proposals?

Join Tufts CTSI for a One Health Workshop on Tuesday, October 4, 9:00AM-1:45PM, at Tufts University School of Dental Medicine, Rachel’s Amphitheater (1 Kneeland Street, 14th Floor, Boston). A live webcast will also be available: the link will only be available to people who RSVP for the event.

Please RSVP here by Friday, September 30.


  • 8:30AM: Registration and light breakfast
  • 9:00AM: Introduction
  • 9:30AM: Project presentations
  • 10:30AM: Break
  • 10:45AM: Project presentations
  • 11:45AM: Introduction to breakout sessions
  • 12:00PM: Lunch and group breakout sessions
  • 1:15PM: Report-back, summary, evaluation, and next steps


The workshop will focus on the following four projects, with the objective of assisting teams to develop proposals for future grant submission:

  • Development of a Safe, Inexpensive, Easily Administered EHEC Vaccine for Cattle
    Project team: John Leong, MD, PhD; Abraham L. Sonenshein, PhD; Saul Tzipori, DVM, PhD, DSc
  • A Novel Approach to Asthma Therapy: Decreasing Airway Smooth Muscle Mass – A One Health Approach Using Naturally Occuring Models of Disease in the Horse and Cat
    Project team: Melissa R. Mazan, DVM; Heber Nielsen, MD
  • Antibiotic Stewardship and Infection Control: Sharing Approaches from Tufts Medical Center and the Foster Hospital for Small Animals at the Cummings School of Veterinary Medicine, and the Effects of the Human Microbiota Due to Bet Antimicrobial Therapy
    Project team: Shira Doron, MD; Kirthana R. Beaulac, PharmD; Tine Vindenes, MD; Annie Wayne, DVM
  • Cohabitation with Production Animals, Gut Microbiota, and Stunting in Children
    Project team: Janet Forrester, PhD; Honorine Ward, MD; Marieke Rosenbaum, DVM

Proposals address one of the four main areas of One Health:

  • Zoonotic and environmentally-induced diseases
  • Diseases shared by humans and other animals (e.g., cancer, heart disease, obesity, arthritis)
  • Challenges and solutions at the intersection of humans, animals, and the environment
  • Human-animal interactions.

Funding Opportunity

Investigators who attend the One Health workshop may be eligible for planning grants ($500) and pilot grants (up to $5,000) to assemble a team and develop One Health research projects. The criteria and process for applying for these funds will be provided at the Workshop. Sign up by September 30 to attend.


For more information, please contact John Castellot, PhD, Tufts CTSI Navigator.

Seminars & Workshops
To Resubmit or Not: Considerations and Next Steps When Your Proposal Isn’t Funded

Did you miss the payline for funding your NIH Proposal? Need help interpreting reviews and deciding when is best to revise and resubmit?

Join Tufts CTSI and the Tufts University Office of Research Development, part of the Office of the Vice Provost for Research, for this valuable one-hour seminar and panel discussion focusing on best practices for surviving peer review and successfully resubmitting an NIH proposal. Seasoned PIs will review reasoning and rationale behind changes they have made in response to study section review. Drawing on insights they have gained as applicants, reviewers, and mentors, they will delve into approaches to evaluating Summary Statements, tailoring responses, and rethinking aims. With expertise spanning the basic-to-clinical research spectrum, panelists will bring a wide range of perspectives on using critiques to improve a study whether in the lab or in the clinic. Topics will include:

  • Interpreting reviewer comments
  • Deciding whether to resubmit
  • Understanding what needs to be changed
  • Framing the Introduction and responding to specific criticisms
  • Avoiding common problems in resubmissions
  • Finding resources or collaborators to strengthen the research plan

Panelists will include:

  • Marta Gaglia, PhD, Assistant Professor of Molecular Biology & Microbiology, Sackler School of Graduate Biomedical Sciences
  • Caroline Genco, PhD, Arthur E Spiller Professor & Chair of Immunology, Sackler School of Graduate Biomedical Sciences
  • Cheryl London, DVM, PhD, Anne Engen and Dusty Professor in Comparative Oncology, Cummings School of Veterinary Medicine


January 24, 2019, 2:00–3:00 PM
35 Kneeland Street, Boston MA
8th Floor Large Conference Room


This program is open to all early career investigators, clinical and/or research fellows, and seasoned PIs from Tufts CTSI partner institutions. Any researcher considering their options for a recent unfunded proposal to NIH or similar funding agencies is welcome to attend.

Please register here by January 18, 2019.

Learning Objectives

After attending this session, participants should be able to:

  • Interpret common reviewer comments
  • Identify key factors to assess when considering a resubmission
  • Recognize items reviewers may look for in resubmitted proposals
  • Identify Tufts University and Tufts CTSI resources to help strengthen your application

Tufts CTSI Professional Education & Expectation for Course Participants

Tufts CTSI’s Professional Education programs provide non-degree continuing education and training for clinical and translational research professionals from all Tufts CTSI partners and beyond.

Course enrollment priority is given to researchers from Tufts CTSI partner institutions. If your participation needs to be approved by your supervisor or a person responsible for your time release, you may provide their contact information when you register for the program.

This course is provided free of charge, and was supported by the National Center for Advancing Translational Sciences, National Institutes of health, Award Number UL1TR002544. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Seminars & Workshops
Zoobiquity Boston Session 2: Obesity in a 12-year-old female domestic shorthair cat and a 64-year-old female pharmacist

After completing this lecture, you will be able to:

  • Compare and contrast obesity in an elderly female patient and obesity in a domestic shorthair cat
  • Discuss the treatments that were used for the female patient versus the domestic shorthair cat
  • Explain how animals can serve as models for human obesity.
Seminars & Workshops
Zoobiquity Boston Session 3: Anterior Cruciate Ligament Injury in a Three-year-old Laborador Retriever and a 21-year-old Competitive Skier

After completing this lecture, you will be able to:

  • Compare and contrast obesity in an elderly female patient and obesity in a domestic shorthair cat
  • Discuss the treatments that were used for the female patient versus the domestic shorthair cat
  • Explain how animals can serve as models for human obesity.