Conferences & Symposia
2016 Comparative Effectiveness Research Symposium: Introduction and What’s Next

After completing this lecture, you will be able to:

  • Define Tufts CTSI’s mission and purpose
  • Describe Explanatory versus Pragmatic trials
  • Identify the components of ‘Team Science’ that are available within the Tufts CTSI

Taught by John Wong, MD, and Harry P. Selker, MD, MSPH

Conferences & Symposia
4th Annual Comparative Effectiveness Research (CER) Symposium Plus

Interested in comparative effectiveness research (CER)? Want to meet collaborators and develop grant proposals?

Join Tufts CTSI for our 4th Annual CER Symposium Plus on Wednesday, June 7, 9:00AM-3:00PM in room 114 (145 Harrison Avenue, Boston). This interactive event will focus on several CER use cases, with the goals of assisting teams to develop research project proposals for future grant submissions, and engaging event participants in team science approaches to catalyze research ideas.


8:30AM: Registration

9:00AM: Introduction

9:30AM: Project Presentations

  • Structured Opioid Use After Joint Arthroplasty submitted by Geneve M. Allison, MD, MSc, FACP, Tufts Medical Center
  • Modeling Spatiotemporal Contributors to Inter-Facility Clostridium Difficile Colitis Transmission submitted by Luke Muggy, PhD, RAND Corporation

10:30AM: Break

10:45AM: Project Presentations

  • Triggers for Palliative Care Engagement: A Comparative Effectiveness Study submitted by Signe Peterson Flieger, PhD, MSW, Tufts University
  • Linkage to HCV Treatment for People with Substance Use Disorders: A Comparative Effectiveness Research Study submitted by Thomas J. Stopka, PhD, Tufts University

11:45AM: Lunch and Networking

12:15PM: Introduction to Breakout Working Groups

12:30PM: Breakout Working Groups

2:00PM: Report-back, Summary, and Next Steps

2:30PM: Evaluations and Adjourn


By the end of this interactive symposium, you will be able to:

  • Describe how CER can help patients, clinicians, and other stakeholders identify the right treatment for a specific patient and a specific time.
  • Value peer and expert feedback as helpful in developing a team science proposal.
  • Describe how researchers presenting at Symposium Plus meetings can work with the CTSI toward submitting a fundable research proposal.
  • Identify the components of a successful CER research proposal.

All are welcome to attend! Please RSVP here.


Wednesday, June 7, 9:00AM-3:00PM
Tufts Center for Medical Education, Room 114
145 Harrison Avenue, Boston MA

Seminars & Workshops
Comparative Effectiveness Research: Where are We Going?

After completing this lecture, you will be able to:

  • Describe the current state of health care
  • List the stages of Comparative Effectiveness Research at Tufts CTSI
  • Explain what is the Patient-Centered Outcomes Research Institute
  • Describe how clinical data research networks can impact Comparative Effectiveness Research.

Taught by: John B. Wong, MD

Conferences & Symposia
Evidence and the Individual Patient: Understanding Heterogeneous Treatment Effects for Patient-Centered Care


This conference will explore the inherent limitations of using group data to guide treatment decisions for individuals. Topics will include examining HTE as it pertains to personalized decision making and precision medicine, modifying care in light of more personalized evidence, and identifying the highest policy and research priorities to facilitate translation and dissemination of these methods. This conference will take a broad view of personalized/precision medicine that seeks to take into account the full gamut of patient-level variation (i.e. not just genetic/pharmacogenetic variation). Conference participants will include thought leaders and stakeholders who are developing and promulgating methods for more individualized evidence from academic, government and regulatory sectors.

Register for the live webcast here.




Seminars & Workshops
Feedback & Assessment: An Essential Ingredient in Comparative Effectiveness Research

After completing this lecture, you will be able to:

  • Understand the role researchers play in a learning healthcare community
  • Appreciate the implications of feedback and assessment from a systems perspective
  • Identify three example of policy resistance in healthcare research, as well as the role of feedback loops in each
  • Appreciate the range of research methods applicable to feedback and assessment in comparative effectiveness research.

Taught by: R. Christopher Sheldrick, PhD

Seminars & Workshops
Making Research Useful: Dissemination and Application of Findings from Comparative Effectiveness Research

After completing this lecture, you will be able to:

  • List the reasons for dissemination and application
  • Identify the users and producers of dissemination and application
  • Appreciate the role of dissemination and application in Comparative Effectiveness Research (CER)
  • Identify potential barriers to dissemination and application of CER
  • Identify strategies to achieve dissemination and application of CER.

Taught by: Dominic Hodgkin, PhD

Seminars & Workshops
Methods for Prioritizing Research in Comparative Effectiveness Research

After completing this lecture, you will be able to:

  • Explain the role of evidence prioritization in comparative effectiveness research
  • Describe the components of evidence prioritization
  • Identify the users and producers of evidence prioritization
  • Define how AHRQ conducts evidence prioritization
  • Discuss how the value of information assists with evidence prioritization as part of health technology assessment.

Taught by: Peter Neumann, ScD, Ethan M. Balk, MD, MPH, and Joshua T. Cohen, PhD

Seminars & Workshops
Systematic Review and Meta-Analysis of Diagnostic Test Studies

After completing this lecture, you will be able to:

  • State how to measure diagnostic test accuracy
  • List the components of a systematic review of diagnostic test studies
  • List types of bias in diagnostic test studies
  • Identify the basic approaches to meta-analysis of diagnostic test studies.

Taught by: Ethan Balk, MD, MPH and Norma Terrin, PhD

Conferences & Symposia
The HELPS-HD Trial: A Cluster Randomized Pragmatic Trial of Oral Protein Supplements by DCI and Demystifying Pragmatic Clinical Trials

After completing this lecture, you will be able to:

  • Outline the impact of protein catabolism during HD
  • Indicate the HELPS-HD study design
  • Describe key factors that distinguish pragmatic trials from explanatory trials

Taught by Daniel Weiner, MD, MS and Thomas Concannon, PhD

Seminars & Workshops
Why Comparative Effectiveness Research Matters

After completing this lecture, you will be able to:

  • List the six steps of the Tufts CTSI Translational Spectrum of Comparative Effectiveness Research (CER)
  • Identify national (NIH, IOM, PCORI) CER priorities
  • Explain the importance of incorporating CER into grant submissions and research
  • Discuss examples of CER research projects

Taught by: John B. Wong, MD