The CTSA Consortium Trial Innovation Network (TIN) is a national collaborative of the CTSA hubs along with three Trial Innovation Centers (TICs), including the Johns Hopkins-Tufts TIC (JHU-Tufts TIC) and a Recruitment Innovation Center (RIC) that supports the development and conduct of multi-site clinical trials across the CTSA Consortium.

To facilitate the quality and success of these trials, the TIN offers investigators the opportunity to request an initial consultation or resources to support a multi-site trial, whether funded or in the planning stages.

The TIN features single IRB capacity, master clinical trial contracting agreements, quality-by-design approaches, innovative study designs, and a focus on evidencebased strategies to recruitment and patient engagement.

Who is eligible?

After receiving local prior approval, investigators who are proposing or who have multi-site clinical trials or studies are eligible to submit a consultation request to the TIN.

TIN requests are vetted and a subset is selected to receive services. Please note that prior to submitting a TIN Project Proposal, investigators must first discuss the proposal with the Tufts MCRC liaison team and receive approval.

Proposal Submissions

The Trial Innovation Network is accepting competitive submissions of requests for research proposal support on an ongoing basis. Selected proposals will receive assistance from national clinical studies experts with developing statistical analysis plans, feasibility analysis, recruitment plans, and guidance on operating a central IRB, among other services.

To learn about services offered by the Trial Innovation Network, and the submission process, please:

Prior to submitting a request for Trial Innovation Network support, investigators must review their study proposals with Tufts CTSI Hub Liaison Team members and avail themselves of available local CTSI protocol development resources. Proposals must be approved by Jonathan Davis, MD, Director of the Trial Innovation Network Hub Liaison Team, before they are submitted to the Trial Innovation Network.

If you are affiliated with Tufts CTSI, please submit a request for support here. Please be sure to select General Consult and use the text box to describe your Trial Innovation Network request.


For more information, please contact:

Jonathan Davis, MD
Director, Trial Innovation Network Hub Liaison Team

Marisha Palm, PhD
Project Director