The diagram depicts the six phases in the Translational Spectrum of Comparative Effectiveness Research:
- Evidence Prioritization: Qualitative and Quantitative Elicitation
- Evidence Generation: Randomized Controlled Trials, Registries, Observational Studies, and N-of-1 Trials
- Evidence Synthesis: Systematic Reviews and Meta-Analysis
- Evidence Interpretation and Integration: Cost-Effectiveness Analysis and Decision Analysis
- Dissemination and Application: Guidelines, Policy, Social Sciences, and Implementation Science
- Feedback and Assessment: Qualitiative Elicitation, Data Monitoring, and Quality Monitoring and Measurement
Each phase relates back to the previous phase(s), and involves researchers, research organizations, and stakeholders.