The table presents a list of submission components, outlining a full application cycle from Letter of Intent to project launch. Applicants will work towards developing a nearly complete package required for prior approval by funding agency NCATS, with each application step serving as a building block.

The Letter of Intent step involves submission of the following components:

  • Project summary
  • Background and significance
    • Project rationale
    • Potential benefits of the proposed research
    • Importance of the knowledge gained
    • Description of translational path
  • Specific aims
    • Primary and secondary aims
  • Project feasibility statement
  • Key personnel
    • Names and affiliation

The Proposal step involves submission of the following components:

  • Project summary
  • Background and significance
    • Project rationale
    • Potential benefits of the proposed research
    • Importance of the knowledge gained
    • Description of translational path
  • Specific aims
    • Primary and secondary aims
  • Project feasibility statement
  • Key personnel
    • Names and affiliation
    • Biosketch(es)
  • Project abstract
  • Research procedures
  • Stakeholder engagement plan
  • Applicant authorization and approval form
  • Project budget

The post-award NCATS step involves submission of the following components (for human and animal subject research):

  • Project summary
  • Background and significance
    • Project rationale
    • Potential benefits of the proposed research
    • Importance of the knowledge gained
    • Description of translational path
  • Specific aims
    • Primary and secondary aims
  • Project feasibility statement
  • Key personnel
    • Names and affiliation
    • Biosketch(es)
  • Research procedures
  • Project budget
  • Certification of IRB/IACUC approval (as applicable)
  • For clinical trials and greater than minimal risk human subject studies:
    • Human subjects training certificate(s)
    • Study protocol
    • Protection and monitoring plan
    • Protocol synopsis (for clinical trials only)