The Online Certificate Program is not currently being offered. 


Tufts CTSI is delighted to offer its first Online Graduate Certificate Program, Fundamentals of Clinical Care Research. The Fundamentals of CCR program offers an introduction to the core elements of clinical research, including clinical epidemiology, study design, biostatistics, and methods that are key to the conduct of evidence-based medicine and comparative effectiveness research. This one year, 2.5 credit program (at a cost of $3333 per credit) features a flexible, online curriculum designed to accommodate the schedules of learners who are already immersed in professional careers or other training programs. The program is ideal for learners who are interested in strengthening their ability to interpret clinical research findings, are considering a master’s or doctoral degree program in public health or clinical research, or need formal research training for their work in the academic, biotech or pharmaceutical sector. Clinicians at Tufts-affiliated hospitals, international students, and professionals in the pharmaceutical and biotechnology industries are especially encouraged to apply.

Who is eligible?

Applicants for the Fundamentals of Clinical Care Research Certificate should hold an advanced biomedical degree (professional, doctoral, or master’s degree) in a health-related field. Exceptionally talented candidates with a bachelor’s degree (or non-US equivalent) in the sciences and a demonstrated interest in clinical research will also be considered.


  • Flexible online format is perfect for local or global participation.
  • Only one course required per semester.
  • Students will experience live webinars, active discussion boards, and asynchronous lectures.
  • Program faculty are experts in clinical investigation, clinical epidemiology, health services research, outcomes research, meta-analysis, biostatistics, and related fields.
  • No thesis required.

Courses & Faculty

The Fundamentals of Clinical Care Research Program will provide students with a basic introduction to clinical research consisting of three courses:

Survey of Clinical Care Research (.5 credit): Summer

David M. Kent, MD, CM, MSc, Program Director

This course offers an introduction to contemporary topics and instruments in clinical care research, with a focus on the role of outcomes research, health economics, systematic reviews and clinical decision making in clinical and translational science. Foundational concepts in clinical trial design (pragmatic and explanatory), meta-analysis and systematic review, health services research, bench-to-bedside translational research, decision analysis, pharmaco-economics and prediction models are surveyed by nationally-known program faculty. This course also reinforces and applies core concepts in biostatistics and epidemiology by illustrating how study designs and statistical approaches may be applied in the context of these designs and analytic approaches, as well as highlighting pitfalls to certain applications. Faculty will foster discussion of applications of these concepts and methods to the primary medical literature during webinars.

Principles of Biostatistics for Clinical Research (1 credit): Fall

Angie Mae Rodday, PhD, MS, Assistant Professor

This course introduces the basic principles and applications of statistics, as they are applied to problems in clinical research. The emphasis is on developing an understanding of the assumptions, limitations, practical considerations and critical thinking in the use of statistical methods in data arising from continuous, binary, and time-to-event data. This course will also introduce biostatistical modeling with a focus on multivariate regression methods. Through webinars, the course will include data exercises and class discussion of articles from the scientific literature that apply methods covered in lectures.

Elements of Epidemiology for Clinical Research (1 credit): Spring

Jessica Paulus, ScD

This course serves as an introduction to topics in epidemiologic study design and analysis, with a focus on those relevant to clinical epidemiology and comparative effectiveness research. After examining the randomized clinical trial as a paradigm, the course reviews the major observational designs, including ecologic, cross-sectional, cohort, and case-control studies. For each study design, relevant sampling and analytical strategies, measures of association and the attendant biases will be covered. Principles and methods will be illustrated through interactive webinars that include discussion of articles from the literature, data analytic exercises, and a causal diagram lab.


To Apply

Click here to start your online application.

Have questions? Contact Elizabeth Leary, PhD, Senior Program Manager.