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CTSI members gathered at a conference

Our Leadership

Harry P. Selker, MD, MSPH

Harry Selker

Dr. Selker is Dean of the Tufts University-wide Clinical and Translational Science Institute (Tufts CTSI) and Principal Investigator the NIH Clinical and Translational Science Award (CTSA) that supports it ( He is Professor of Medicine at the Tufts University School of Medicine and Executive Director for the Institute for Clinical Research and Health Policy Studies at Tufts Medical Center, where he is also Chief of the Division of Clinical Care Research in the Department of Medicine and Director of the Center for Cardiovascular Health Services Research.

He also has served on boards and as an officer for a variety of professional and educational organizations, including in 2011-2012 as President of the Society of General Internal Medicine, 2010-2011 as President of the Society for Clinical and Translational Science and 2003-2004 as President of the Association for Clinical Research Training. He has been an active advisor in the design of Clinical Research graduate and training programs in the United States and internationally, and he is an active advocate and advisor in Washington in support of clinical research, research training, and for improvements in the healthcare delivery system. He maintains his medical practice at the Pratt Diagnostic Clinic at Tufts Medical Center.

In his research, Dr. Selker is particularly known for a series of studies of the factors influencing emergency cardiac care and for development of "cardiac predictive instruments," mathematical models embedded into electrocardiographs, as decision aids that provide emergency clinicians with predictions of key outcomes for real-time use in the clinical setting. This has included methodological development of mathematical modeling of medical outcomes for risk adjustment and clinical prediction. He was Principal Investigator and Study Chair for the NIH National Heart Lung and Blood-sponsored national IMMEDIATE (Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency care) Trial of the use of intravenous GIK (glucose, insulin, and potassium) delivered by paramedics in the community to reduce mortality from acute coronary syndromes and infarction. He also was Principal Investigator for a multicenter study of error reduction approaches in emergency medical service and emergency department care, being done in Massachusetts communities jointly by their local hospitals and EMS systems. He has been continuously funded by federal R01 and equivalent grants for over two decades.